Urinary mandelic acid and hemoglobin adducts in fiberglass-reinforced plastics workers exposed to styrene.
نویسندگان
چکیده
منابع مشابه
Determination of albumin and hemoglobin adducts in workers exposed to styrene and styrene oxide.
Hemoglobin and albumin adducts of the carcinogen styrene-7,8-oxide (SO) were measured in 48 workers exposed to both styrene and SO in a boat manufacturing plant. Personal exposures to both substances were measured repeatedly over the course of 1 year (styrene:0.9-235 mg/m3 with a mean of 64.3 mg/m3 for 48 subjects; S0: 13.4-525 mu g/m3 with a mean of 159 mu g/m3 for 20 subjects). Cysteine and c...
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Nitrotoluenes are important intermediates in the chemical industry. 2,6-Dinitrotoluene (26DNT), 2,4-dinitrotoluene (24DNT) and 2-nitrotoluene are carcinogenic in animals and possibly carcinogenic in humans. It is therefore important to develop methods to biomonitor workers exposed to such chemicals. Hemoglobin (Hb) adducts of nitroarenes are established markers of the biological effective dose....
متن کاملStudy of urinary concentrations of mandelic acid in employees exposed to styrene.
Mandelic acid (MA) is an important metabolite of styrene. In humans, measurement of its concentration in urine provides an important assessment of the overall level of styrene exposure in workers of the reinforced plastic manufacturing industry. The aim of our study was to investigate in these workers the relationship between MA concentration and styrene exposure time and intensity as well as i...
متن کاملHemoglobin adducts in workers exposed to benzidine and azo dyes.
Benzidine (Bz) is a known human carcinogen. Several azo dyes have been synthesized with Bz. Bz can be metabolically released from azo dyes. In a group of Indian workers producing Bz and azo dyes the presence of hemoglobin (Hb) adducts was investigated. The following Hb adducts were identified and quantified by GC-MS: Bz, N-acetylbenzidine (AcBz), 4-aminobiphenyl (4ABP), aniline. 4ABP and anilin...
متن کاملExposure assessment of monoterpenes and styrene: a comparison of air sampling and biomonitoring.
BACKGROUND Within- and between-worker variance components have seldom been reported for both environmental and biological data collected from the same persons. AIMS To estimate these variance components and their ratio for air contaminants and urinary metabolites in two different work environments and to predict the attenuation of exposure-response relationships based on these measures. MET...
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ژورنال
عنوان ژورنال: Scandinavian Journal of Work, Environment & Health
سال: 1994
ISSN: 0355-3140,1795-990X
DOI: 10.5271/sjweh.1375